Molecular Physiology & Biophysics



Current Research Projects

  • Structural-functional study of ion channels and receptors.
  • Study of biomolecular sensors (voltage, temperature, pH, redox and mechanical stress).
  • Channelopathy (arrhythmia, paralysis, pain, etc.)

Recent Publications

  • Structural Insights into Divalent Cation Modulations of ATP-Gated P2X Receptor Channels.
    Kasuya G, Fujiwara Y. et al. Cell Reports,14:932-944 (2016).
  • Long α-helices projecting from the membrane as the dimer interface in the voltage-gated H+ channe.
    Fujiwara Y. et al. J. Gen. Physiol. 143, 337-386 (2014).
  • The cytoplasmic coiled-coil mediates cooperative gating temperature sensitivity in the voltage-gated H+ channel Hv1
    Fujiwara Y. et al. Nature Communications. 3, 816 (2012).

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