Radiation Oncology

Basic and clinical research to improve quality and efficacy of intensity modulated radiation therapy (IMRT) by achieving highly-optimized dose distributions and to promote its application to a wide range of cancers, including head and neck cancers, malignant glioma, prostate cancers, and uterine cervical cancers.
Studies on quality assurance of verification and high precision radiation delivery by image-guided radiotherapy (IGRT) using real-time imaging technology.
Studies on contouring targets and risk organs by automatic and deformable image registration technology as well as image fusion technology using CT, MRI, and various molecular images.
Studies on mechanism of treatment-related toxicity of normal tissues (i.e., radiation pneumonitis) and on its reduction via eliminating unnecessary dose by IMRT, IGRT, and respiratory gating technology.
Participation and co-operation in nationwide clinical research trialists group as follows:JCOG (Japan Clinical Oncology Group), WJOG (West Japan Oncology Group), JROSG (Japanese Radiation Oncology Study Group)

A retrospective study of locally advanced cervical cancer cases treated with CT-based 3D-IGBT compared with 2D-IGBT. Kinoshita T, Takahashi S, Anada M, et al. Jpn J Radiol. 2023;41:1164-1172.
Prospective Exploratory Study of the Relationship Between Radiation Pneumonitis and TGF-β1 in Exhaled Breath Condensate. Takahashi S, Anada M, Kinoshita T, et al. In Vivo. 2022;36:1485-1490.
Impact of rotational errors of whole pelvis on the dose of prostate-based image-guided radiotherapy to pelvic lymph nodes and small bowel in high-risk prostate cancer. Katayama H, Takahashi S, Kobata T, et al. Rep Pract Oncol Radiother. 2021;26:906-914.

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