欧文原著論文

岩間久和のホームページへ

• "The antidiabetic drug metformin inhibits gastric cancer cell proliferation in vitro and in vivo."
  Kiyohito K, Gong J, Iwama H, Kitanaka A, Tani J, Miyoshi H, Nomura K, Mimura S, Kobayashi M, Aritomo Y, Kobara H, Mori H, Himoto T, Okano K, Suzuki Y, Murao K, Masaki T.
  Mol Cancer Ther 2012 in Press.
  
  
• "Novel Mutations in the Gene Encoding Acid α-1,4-glucosidase in a Patient with Late-onset Glycogen Storage Disease Type II (Pompe Disease) with Impaired Intelligence."
  Muraoka T, Murao K, Imachi H, Kikuchi F, Yoshimoto T, Iwama H, Hosokawa H, Nishino I, Fukuda T, Sugie H, Adachi K, Nanba E, Ishida T.
  Int Med 2011 50(24):2987-91.
  
  
• "Transcriptional double-autorepression feedforward circuits act for multicellularity and nervous system development."
  Iwama H, Murao K, Imachi H, Ishida T.
  BMC Genomics 2011 12:228.
  
  
• “Frequent loss of p19INK4D expression in hepatocellular carcinoma: relationship to tumor differentiation and patient survival.”
  Morishita A, Gong J, Deguchi A, Tani J, Miyoshi H, Yoshida H, Himoto T, Yoneyama H, Mori H, Kato K, Kurokohchi K, Deguchi K, Izuishi K, Suzuki Y, Kushida Y, Haba R, Iwama H, Watanabe S, D'Armiento J, Masaki T.
  Oncol Rep. 2011 26(6):1363-8.
  
  
• "Exendin-4 regulates the expression of the ATP-binding cassette transporter A1 via transcriptional factor PREB in the pancreatic β cell line."
  Miyai Y, Murao K, Imachi H, Li J, Nishiuchi Y, Masugata H, Iwama H, Kushida Y, Ishida T, Haba R.
  J Endocrinol Invest 2011 34(9):e268-74
  
  
• "MicroRNA Networks Alter to Conform to Transcription Factor Networks Adding Redundancy and Reducing the Repertoire of Target Genes for Coordinated Regulation."
  Iwama H, Murao K, Imachi H, Ishida T.
  Mol Biol Evol. 2011 28(1):639-46.
  
  
• "Use of protein array technology to investigate receptor tyrosine kinases activated in hepatocellular carcinoma."
  Liu, S., Gong, J., Morishita, A., Nomura, T., Miyoshi, H., Tani, J., Kato, K., Yoneyama, H., Deguchi, A., Mori, H., Mimura, S., Nomura, K., Himoto, T., Deguchi, K., Okano, K., Izuishi, K., Suzuki, Y., Kushida, Y., Haba, R., Iwama, H., and Masaki, T.
  Exp Ther Med. 2011 2: 399-403.
  
  
• "The transcription factor prolactin regulatory element-binding protein mediates prolactin transcription induced by thyrotropin-releasing hormone in GH3 cells."
  Yu X, Murao K, Imachi H, Li J, Nishiuchi T, Dobashi H, Hosomi N, Masugata H, Zhang GX, Iwama H, Ishida T.
  Endocrine. 2010 38(1):53-9.
  
  
• "Transcriptional factor prolactin regulatory element-binding protein-mediated gene transcription of ABCA1 via 3',5'-cyclic adenosine-5'-monophosphate."
  Nishiuchi Y, Murao K, Imachi H, Nishiuchi T, Iwama H, Ishida T.
  Atherosclerosis. 2010 212(2):418-25.
  
  
• "Suppression of prolactin expression by cabergoline requires prolactin regulatory element-binding protein (PREB) in GH3 cells."
  Zhang W, Murao K, Imachi H, Iwama H, Chen K, Fei Z, Zhang X, Ishida T, Tamiya T.
  Horm Metab Res. 2010 42(8):557-61.
  
  
• "Hyperglycemia suppresses ABCA1 expression in vascular smooth muscle cells."
  Yu X, Murao K, Imachi H, Li J, Nishiuchi T, Hosomi N, Masugata H, Zhang GX, Iwama H, Ishida T.
  Horm Metab Res. 2010 42(4):241-6.
  
  
• "Exendin-4 regulates pancreatic ABCA1 transcription via CaMKK/CaMKIV pathway."
  Li J, Murao K, Imachi H, Masugata H, Iwama H, Tada S, Zhang GX, Kobayashi R, Ishida T, Tokumitsu H.
  J Cell Mol Med. 2010 14(5):1083-7.
  
  
• "Use of protein array to investigate receptor tyrosine kinases activated in gastric cancer."
  Gong J, Morishita A, Kurokohchi K, Tani J, Kato K, Miyoshi H, Inoue H, Kobayashi M, Liu S, Murota M, Muramatsu A, Izuishi K, Suzuki Y, Yoshida H, Uchida N, Deguchi K, Iwama H, Ishimaru I, Masaki T.
  Int J Oncol. 2010 36(1):101-6.
  
  
• "The prolactin regulatory element-binding regulates of the 11beta-hydroxylase gene."
  Imachi H, Murao K, Cao WM, Muraoka T, Nishiuchi T, Dobashi H, Hosomi N, Iwama H, Ishida T.
  Biochem Biophys Res Commun. 2008 376(3):531
  
  
• "Annexin A2 expression and phosphorylation are up-regulated in hepatocellular carcinoma."
  Mohammad HS, Kurokohchi K, Yoneyama H, Tokuda M, Morishita A, Jian G, Shi L, Murota M, Tani J, Kato K, Miyoshi H, Deguchi A, Himoto T, Usuki H, Wakabayashi H, Izuishi K, Suzuki Y, Iwama H, Deguchi K, Uchida N, Sabet EA, Arafa UA, Hassan AT, El-Sayed AA, Masaki T.
  Int J Oncol. 2008 33(6):1157
  
  
• "The transcriptional factor prolactin regulatory element-binding protein mediates the gene transcription of adrenal scavenger receptor class B type I via 3',5'-cyclic adenosine 5'-monophosphate."
  Murao K, Imachi H, Yu X, Cao WM, Muraoka T, Dobashi H, Hosomi N, Haba R, Iwama H, Ishida T.
  Endocrinology. 2008 ;149(12):6103
  
  
• "ReAlignerV: Web-based genomic alignment tool with high specificity and robustness estimated by species-specific insertion sequences."
  Iwama H, Hori Y, Matsumoto K, Murao K, Ishida T.
  BMC Bioinformatics. 2008 9(1):112
  
  
• "The role of calcium/calmodulin-dependent protein kinase cascade on MIP-1alpha gene expression of ATL cells."
  Matsumoto K, Murao K, Imachi H, Nishiuchi T, Cao W, Yu X, Li J, Ahmed RA, Iwama H, Kobayashi R, Tokumitsu H, Ishida T.
  Exp Hematol. 2008
  
  
• "Evola: Ortholog database of all human genes in H-InvDB with manual curation of phylogenetic trees."
  Matsuya A, Sakate R, Kawahara Y, Koyanagi KO, Sato Y, Fujii Y, Yamasaki C, Habara T, Nakaoka H, Todokoro F, Yamaguchi K, Endo T, Oota S, Makalowski W, Ikeo K, Suzuki Y, Hanada K, Hashimoto K, Hirai M, Iwama H, Saitou N, Hiraki AT, Jin L, Kaneko Y, Kanno M, Murakami K, Noda AO, Saichi N, Sanbonmatsu R, Suzuki M, Takeda J, Tanaka M, Gojobori T, Imanishi T, Itoh T.
  Nucleic Acids Res. 2008 36(Database issue):D787-92
  
  
• "Abundance of microRNA target motifs in the 3'-UTRs of 20527 human genes."
  Iwama H, Masaki T, Kuriyama S.
  FEBS Lett. 2007 581(9):1805-10.
  
  
• "Identification of c-Yes expression in the nuclei of hepatocellular carcinoma cells: Involvement in the early stages of hepatocarcinogenesis."
  Nonomura T, Masaki T, Morishita A, Jian G, Uchida N, Himoto T, Izuishi K, Iwama H, Yoshiji H, Watanabe S, Kurokohchi K, Kuriyama S.
  Int J Oncol. 2007 30:105-11
  
  
• "Activation of c-Yes in hepatocellular carcinoma: a preliminary study"
  Feng H, Masaki T, Nonomura T, Morishita A, Jian G, Nakai S, Deguchi A, Uchida N, Himoto T, Iwama H, Usuki H, Wakabayashi H, Izuishi K, Yoshiji H, Kurokohchi K, Kuriyama S.
  World J Gastroenterol. 2006 12:5743-5.
  
  
• "Prolactin regulatory element binding protein as a potential transcriptional factor for the insulin gene in response to glucose stimulation"
  Ohtsuka S, Murao K, Imachi H, Cao WM, Yu X, Li J, Iwama H, Wong NC, Bancroft C, Ishida T.
  Diabetologia. 2006 49:1599-607
  
  
• "The map-based sequence of the rice genome"
  International Rice Genome Sequencing Project.
  Matsumoto, T. et al. ---------- (Area of Physical Maps and Sequencing)
  Iwama, H., Gojoboti T. et al. ---- (Area of Annotation and Analysis)
  Benjamin, B. ---------------- (Coordination)
  Nature 2005 436:793-800
  
  
• “Structural and Functional Analysis of a 0.5-Mb Chicken Region Orthologous to the Imprinted Mammalian Ascl2/Mash2-Igf2-H19 Region.”
  Yokomine, T, Shirohzu, H, Purbowasito, W, Toyoda, A, Iwama, H, Ikeo, K, Hori, T, Mizuno, S, Tsudzuki, M, Matsuda, Y, Hattori, M, Sasaki, Y and Sasaki, H.
  Genome Res. 2005, 15:154-65
  
  
• “Highly Conserved Upstream Sequences for Transcription Factor Genes and Implications for the Regulatory Network”
  Iwama, H. and Gojobori, T
  Proc. Natl. Acad. Sci. U. S. A. 2004, 101:17156-61
  ==== Top-9 Most-Frequently-Read Article in PNAS during Dec. 2004. ====
  
  
• “The Genome Sequence and Structure of Rice Chromosome 1”
  Sasaki T, Matsumoto T, Yamamoto K, Sakata K, Baba T, Katayose Y, Wu J, Niimura Y, Cheng Z, Nagamura Y, Antonio BA, Kanamori H, Hosokawa S, Masukawa M, Arikawa K, Chiden Y, Hayashi M, Okamoto M, Ando T, Aoki H, Arita K, Hamada M, Harada C, Hijishita S, Honda M, Ichikawa Y, Idonuma A, Iijima M, Ikeda M, Ikeno M, Ito S, Ito T, Ito Y, Ito Y, Iwabuchi A, Kamiya K, Karasawa W, Katagiri S, Kikuta A, Kobayashi N, Kono I, Machita K, Maehara T, Mizuno H, Mizubayashi T, Mukai Y, Nagasaki H, Nakashima M, Nakama Y, Nakamichi Y, Nakamura M, Namiki N, Negishi M, Ohta I, Ono N, Saji S, Sakai K, Shibata M, Shimokawa T, Shomura A, Song J, Takazaki Y, Terasawa K, Tsuji K, Waki K, Yamagata H, Yamane H, Yoshiki S, Yoshihara R, Yukawa K, Zhong H, Iwama H, Endo T, Ito H, Hahn JH, Kim HI, Eun MY, Yano M, Jiang J, Gojobori T.
  Nature 2002, 420:312-316
  
  
• “Identification of Neurotransmitter Receptor Genes under Significantly Relaxed Selective Constraint by Orthologous Gene Comparisons between Humans and Rodents”
  Iwama, H. and Gojobori, T.
  Mol. Biol. Evol. 2002, 19:1891-1901
  
  
• “Epstein-Barr Virus Detection in Kidney Biopsy Specimens Correlates with Glomerular Mesangial Injury”
  Iwama, H., Horikoshi, S., Shirato, I. and Tomino, Y.
  Am. J. Kidney Dis. 1998, 32:785-793
  

和文総説

• 「消化器系疾患の遺伝子学−消化器癌における遺伝子異常」
  栗山茂樹，正木勉，岩間久和
  最新医学　2006　61巻9号　1914-1926
  
  
• 「神経伝達にかかわる蛋白質分子の進化−カテコールアミン受容体とG蛋白αサブユニットを中心にして−．」
  岩間久和，五條堀孝
  蛋白質・核酸・酵素，2001，　46巻11号，pp 1586-1593
  
  
• 「研究資源としてのバイオインフォマティクス．」
  五條堀孝，岩間久和
  ヒューマン・サイエンス，2001,　12巻1号, pp 19-21

著書

• 生命情報学キーノート　（”Instant Notes in Bioinformatics”, D.R. Westhead, J.H. Parish and R.M. Twyman著，池尾一穂、鈴木善幸、五條堀孝　監訳）
  シュプリンガー・フェアラーク東京，2003
  “マイクロアレーのデータ解析” pp175-187，
  “創薬産業における生命情報学“ pp229-234.
  岩間久和　訳
  
  
• 腎臓病の治療と看護　（富野康日己、櫻井美鈴　編）
  南江堂，2000
  “びまん性増殖性糸球体腎炎：Non-IgA腎症” pp 95-100
  岩間久和
  
  
• 思春期精神科症例集
  “行動化は行動の言語的使用(誤用)と言えるか：ある境界例の一症例を通しての考察”，第V章 pp 190-202，1995
  岩間久和

和文原著論文

• 「肝細胞癌におけるmicroRNAのプロファイリング」
  正木勉，　岩間久和， 栗山茂樹
  Acta Hepatologica Japonica 2006 47(suppl2)
  
• 「連携精神医学の臨床的研究−総合病院における精神科コンサルテーションの現状と課題−．」
  栗田有代， 高岡　健， 坂井豊雄， 笠原憲司， 岩間久和， 本間博行， 吉村　剛
  岐阜大学医学部紀要，41巻1号，pp 318-339，1993
  
• 「反社会性人格障害に関する批判的考察−演技性人格障害および境界性人格障害との異同−．」
  高岡　健， 稲田隆司， 岩間久和，杉田憲夫
  臨床精神病理，14巻4号, pp 289-296，1993
  
• 「特異な脳波所見を呈したステロイド精神病の1例．」
  奥野孝代，植木啓文，児玉佳也，高井昭裕，岩間久和，山下元基
  精神医学，34巻10号，pp 1121-1123，1992
  
• 「摂食障害外来．」
  稲田隆司，高岡　健，近藤卓和，岩間久和，大野智裕，小出浩之
  臨床精神医学， 19巻8号，pp 1207-1213，1990