香川大学医学部薬理学

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2012論文

1 New concepts in endothelin control of sodium balance.
Nakano D, Pollock DM.
Clin Exp Pharmacol Physiol. 2012;39(1):104-110.
2 Salt-sensitive hypertension: Introduction.
Nakano D, Mori T.
Clin Exp Pharmacol Physiol. 2012;39(1):87-89.
3 Aldosterone does not contribute to renal p21 expression during the development of angiotensin II-induced hypertension in mice.
Nakano D, Lei B, Kitada K, Hitomi H, Kobori H, Mori H, Deguchi K, Masaki T, Minamino T, Nishiyama A.
Am J Hypertens. 2012 Mar;25(3):354-8.
4 Aldosterone induces insulin-like growth factor-1 receptor and hybrid receptor.
Sherajee SJ, Fujita Y, Rafiq K, Nakano D, Mori H, Masaki T, Hara T, Kohno M, Nishiyama A, Hitomi H.
Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):257-63.
5 Activation of the aldosterone/mineralocorticoid receptor system and protective effects of mineralocorticoid receptor antagonism in retinal ischemia-reperfusion injury.
Liu Y, Hirooka K, Nishiyama A, Bai L, Nakamura T, Itano T, Fujita T, Zhang J, Shiraga F.
Exp Eye Res. 2012 Mar;96(1):116-23.
6 Early treatment with olmesartan prevents juxtamedullary glomerular podocyte injury and the onset of microalbuminuria in type 2 diabetic rats.
Sofue T, Kiyomoto H, Kobori H, Urushihara M, Nishijima Y, Kaifu K, Hara T, Matsumoto S, Ichimura A, Ohsaki H, Hitomi H, Kawachi H, Hayden MR, Whaley-Connell A, Sowers JR, Ito S, Kohno M, Nishiyama A.
Am J Hypertens. 2012 May;25(5):604-11.
7 The optimal timing of antihypertensive medication administration for morning hypertension in patients with cerebral infarction.
Hosomi N, Sueda Y, Masugata H, Dobashi H, Murao K, Ueno M, Miki T, Kohno M, Nishiyama A, Matsumoto M.
Hypertens Res. 2012 Jul;35(7):720-4.
8 Angiotensin receptor blockade increases pancreatic insulin secretion and decreases glucose intolerance during glucose supplementation in a model of metabolic syndrome.
Rodriguez R, Viscarra JA, Minas JN, Nakano D, Nishiyama A, Ortiz RM.
Endocrinology. 2012 Apr;153(4):1684-95.
9 Renal sympathetic denervation suppresses de novo podocyte injury and albuminuria in rats with aortic regurgitation.
Rafiq K, Noma T, Fujisawa Y, Ishihara Y, Arai Y, Navi AHMN, Suzuki F, Nakano D, Hitomi H, Kitada K, Urushihara M, Kobori H, Kohno M, Nishiyama A.
Circulation. 2012 Mar 20;125(11):1402-13.
10 The biphasic time course of the changes in aldosterone biosynthesis under high salt conditions in Dahl salt-sensitive rats.
Morizane S, Mitani F, Ozawa K, Ito K, Matsuhashi T, Katsumata Y, Ito H, Yan X, Shinmura K, Nishiyama A, Honma S, Suzuki T, Funder JW, Fukuda K, Sano M.
Arterioscler Thromb Vasc Biol. 2012 May;32(5):1194-203.
11 Role of angiotensin II-mediated AMPK inactivation on obesity-related salt-sensitive hypertension.
Deji N, Kume S, Araki SI, Isshiki K, Araki H, Chin-Kanasaki M, Tanaka Y, Nishiyama A, Koya D, Haneda M, Kashiwagi A, Maegawa H, Uzu T.
Biochem Biophys Res Commun. 2012 Feb 17;418(3):559-64.
12 Chymase inhibition prevents myocardial fibrosis through the attenuation of NOX4-associated oxidative stress in diabetic hamsters.
Maeda Y, Inoguchi T, Takei R, Hendarto H, Ide M, Inoue T, Kobayashi K, Urata H, Nishiyama A, Takayanagi R.
J Diabetes Investig. 2012 Aug 20;3(4):354-361.
13 Enhanced intrarenal receptor-mediated prorenin activation in chronic progressive anti-thymocyte serum nephritis rats on high salt intake.
Huang Y, Yamamoto T, Misaki T, Suzuki H, Togawa A, Ohashi N, Fujigaki Y, Ichihara A, Nishiyama A, Senbonmatsu T, Ikegaya N, Hishida A.
Am J Physiol Renal Physiol. 2012 Jul;303(1):F130-8. Epub 2012 Apr 11.
14 Liver angiotensinogen is the primary source of renal angiotensin II.
Matsusaka T, Niimura F, Shimizu A, Pastan I, Saito A, Kobori H, Nishiyama A, Ichikawa I.
J Am Soc Nephrol. 2012 Jul;23(7):1181-9. Epub 2012 Apr 19.
15 Add-on aliskiren elicits stronger renoprotection than high-dose valsartan in type 2 diabetic KKAy mice that do not respond to low-dose valsartan.
Lei B, Nakano D, Fan YY, Kitada K, Hitomi H, Kobori H, Mori H, Masaki T, Nishiyama A.
J Pharmacol Sci. 2012 Jun 16;119(2):131-8.
16 Neuroprotective effects of angiotensin II type 1 receptor (AT1-R) blocker via modulating AT1-R signaling and decreased extracellular glutamate levels.
Fujita T, Hirooka K, Nakamura T, Itano T, Nishiyama A, Nagai Y, Shiraga F.
Invest Ophthalmol Vis Sci. 2012 Jun 26;53(7):4099-110. Print 2012.
17 Pre-existing arteriosclerotic intimal thickening in living-donor kidneys reflects allograft function.
Sofue T, Inui M, Kiyomoto H, Moritoki M, Nishioka S, Nishijima Y, Moriwaki K, Hara T, Kushida Y, Haba R, Yoda T, Hirao T, Kakehi Y, Nishiyama A, Kohno M.
Am J Nephrol. 2012 Jul 13;36(2):127-135.
18 N-type calcium channel inhibition with cilnidipine elicits glomerular podocyte protection independent of sympathetic nerve inhibition.
Lei B, Nakano D, Fujisawa Y, Liu Y, Hitomi H, Kobori H, Mori H, Masaki T, Asanuma K, Tomino Y, Nishiyama A.
J Pharmacol Sci. 2012 Aug 18;119(4):359-67.
19 Elucidating mechanisms underlying altered renal autoregulation in diabetes.
Takenaka T, Inoue T, Ohno Y, Miyazaki T, Nishiyama A, Ishii N, Suzuki H.
Am J Physiol Regul Integr Comp Physiol. 2012 Sep;303(5):R495-504.
20 Oxidative stress-induced glomerular mineralocorticoid receptor activation limits the benefit of salt reduction in Dahl salt-sensitive rats.
Kitada K, Nakano D, Liu Y, Fujisawa Y, Hitomi H, Shibayama Y, Shibata H, Nagai Y, Mori H, Masaki T, Kobori H, Nishiyama A.
PLoS ONE. 2012;7(7):e41896. Epub 2012 Jul 24.
21 Multiphoton imaging of the glomerular permeability of angiotensinogen.
Nakano D, Kobori H, Burford JL, Gevorgyan H, Seidel S, Hitomi H, Nishiyama A, Peti-Peterdi J.
J Am Soc Nephrol. 2012 Nov;23(11):1847-56.
22 Loss of the endothelial glycocalyx links albuminuria and vascular dysfunction.
Salmon AH, Ferguson JK, Burford JL, Gevorgyan H, Nakano D, Harper SJ, Bates DO, Peti-Peterdi J.
J Am Soc Nephrol. 2012 Aug;23(8):1339-50.
23 Aldosterone induces p21-regulated apoptosis via increased synthesis and secretion of tumour necrosis factor-α in human proximal tubular cells.
Kitada K, Nakano D, Hitomi H, Kobori H, Deguchi K, Mori H, Masaki T, Nishiyama A.
Clin Exp Pharmacol Physiol. 2012 Oct;39(10):858-63.
24 Angiotensin receptor blockade recovers hepatic UCP2 expression, aconitase and SDH activities, and ameliorates hepatic oxidative damage in insulin resistant rats.
Montez P, Thorwald MA, Rodriguez R, Viscarra JA, Vazquez-Medina JP, Nakano D, Peti-Peterdi J, Nishiyama A, Ortiz RM.
Endocrinology. 2012 Dec;153(12):5746-59.
25 Important aspects of urine sampling for angiotensinogen measurement: time and preservation conditions in healthy individuals.
Nishijima Y, Kobori H, Sofue T, Kaifu K, Moriwaki K, Hara T, Hitomi H, Kohno M, Nishiyama A.
Tohoku J Exp Med. 2012;228(4):333-9.
25 Quantitative Spectroscopic Tomography for the Non-invasive Measurement of the Biogenic-substances.
Wei Qi, Daisuke Kojima, Shun Sato, Satoru Suzuki, Pradeep K. W. Abeygunawardhana, Akira Nishiyama, Ichirou Ishimaru.
MECATRONICS REM. 2012;280-285.
26 The wide-field Fourier spectroscopic-imaging of the radiation heat from the object itself in the middle infrared region for the health monitoring.
Wei Qi, Takashi Takuma, Asuka Inui, Ryosuke Tsutsumi, Takehiko Yuzuriha, Hiroyasu Kagiyama, Daisuke Kojima, Akira Nishiyama, Ichirou Ishimaru.
OPTICAL DIAGNOSTICS AND SENSING XII: TOWARD POINT-OF-CARE DIAGNOSTICS; AND DESIGN AND PERFORMANCE VALIDATION OF PHANTOMS USED IN CONJUNCTION WITH OPTICAL MEASUREMENT OF TISSUE IV 8229
27 Spectroscopic tomography of biological tissues with the near-infrared radiation for the non-invasive measurement of the biogenic-substances.
Daisuke Kojima, Takashi Takuma, Asuka Inui, Wei Qi, Ryosuke Tsutsumi, Takehiko Yuzuriha, Hiroyasu Kagiyama, Akira Nishiyama, Ichirou Ishimaru.
OPTICAL DIAGNOSTICS AND SENSING XII: TOWARD POINT-OF-CARE DIAGNOSTICS; AND DESIGN AND PERFORMANCE VALIDATION OF PHANTOMS USED IN CONJUNCTION WITH OPTICAL MEASUREMENT OF TISSUE IV 8229
28 Aldosterone induces vascular insulin resistance by increasing insulin-like growth factor-1 receptor and hybrid receptor.
Sherajee SJ, Fujita Y, Rafiq K, Nakano D, Mori H, Masaki T, Hara T, Kohno M, Nishiyama A, Hitomi H.
Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):257-63.
29 Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3.
Inoue K, Matsui I, Hamano T, Fujii N, Shimomura A, Nakano C, Kusunoki Y, Takabatake Y, Hirata M, Nishiyama A, Tsubakihara Y, Isaka Y, Rakugi H.
Laboratory Investigation. 2012 Dec;92(12):1686-1697.
30 Angiotensin II receptor blocker improves salt sensitivity of blood pressure and renal nitric oxide synthesis in type 2 diabetic patients with microalbuminuria.
Okada N, Konishi Y, Morikawa N, Maeda I, Kitabayashi C, Masada N, Shirahashi N, Wilcox CS, Nishiyama A, Imanishi M.
J Renin Angiotensin Aldosterone Syst. 2012 May.
31 Activation of JNK Triggers Release of Brd4 from Mitotic Chromosomes and Mediates Protection from Drug-Induced Mitotic Stress.
Nishiyama A, Dey A, Tamura T, Ko M, Ozato K.
PLoS ONE. 2012 May;7(5).
32 Enriched Cholesterol Diet Increases Expression of Renal Epithelial Na+ Channel Gamma Subunit in Rats.
Sood J, Balayan S, Minas JN, Rodriguez R, Aguil J, Nakano D, Nishiyama A, Awayda MS, Ortiz R.
FASEB Journal. 2012 Apr;26.
33 Decreased Pancreatic Insulin Secretion is associated with increased AT1 Activation during Glucose Supplementation in a Model of Metabolic Syndrome.
Rodriguez R, Viscarra JA, Minas JN, Lee A, Nakano D, Nishiyama A, Ortiz RM.
FASEB Journal. 2012 Apr;26.
34 High Dietary Glucose Intake Increases Hepatic Triglyceride Content and Oxidative Stress: Contributions of Angiotensin Receptor.
Montez P, Thorwald AM, Rodriguez R, Viscarra J, Vazquez-Medina JP, Nakano D, Nishiyama A, Ortiz RM.
FASEB Journal. 2012 Apr;26.
35 AT1 blockade decreases NADPH oxidase 2 content and increases insulin signaling in a model of insulin resistance.
Popovich I, Rodriguez R, Viscarra J, Vazquez-Medina JP, Nishiyama A.
FASEB Journal. 2012 Apr;26.
36 Aldosterone induces apoptosis of proximal tubular cells through p21/TNF alpha-dependent pathway.
Kitada K, Nakano D, Yatabe J, Hitomi H, Kobori H, Nishiyama A.
Journal of Pharmacological Sciences. 2012;118:93P-93P.
37 Glomerular mineralocorticoid receptor activation limits the benefits of salt reduction in Dahl salt-sensitive rats.
Nakano D, Kitada K, Liu Y, Fujisawa Y, Hitomi H, Kobori H, Nishiyama A.
Journal of Pharmacological Sciences. 2012;118:93P-93P.
38 Chronic measurement of renal sympathetic nerve activity (RSNA) in rats by using a telemetry system.
Kondo N, Fujisawa Y, Fujita M, Nogami H, Kawakami K, Moritoki M, Nishioka S, Nishijima Y, Sofue T, Kaifu K, Hara T, Kitada K, Nakano D, Kohno M, Nishiyama A.
Journal of Pharmacological Sciences. 2012;118:93P-93P.
39 p21 is central regulator for the development of cell senescence in diabetic proximal tubules.
Kitada K, Nakano D, Yatabe J, Hitomi H, Kobori H, Nishiyama A.
Journal of Pharmacological Sciences. 2012;118:71P-71P.
40 Effects of anesthetic agents on renal sympathetic nerve activity in a freely moving conscious rat.
Fujisawa Y, Kondo N, Nagai Y, Nakano D, Nishiyama A.
Journal of Pharmacological Sciences. 2012;118:239P-239P.
41 Association between cardiac function and pulmonary function in hypertensive patients.
Masugata H, Senda S, Okada H, Murao K, Hitomi H, Hosomi N, Murakami K, Noma T, Nishiyama A, Kohno M.
Department of Integrated Medicine. 2012;40(1):105-114.